Periodical (Journal)

ISSN  :   0027-5107 ( Print )   |   1386-1964 ( Print )   |   1873-135X ( Online )   |   0921-8262 ( Online )   |   1879-2871 ( Online )   Active

Journal Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Aim & Scope

Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis provides a platform for publishing all aspects of DNA mutations and epimutations, from basic evolutionary aspects to translational applications in genetic and epigenetic diagnostics and therapy. Mutations are defined as all possible alterations in DNA sequence and sequence organization, from point mutations to genome structural variation, chromosomal aberrations and aneuploidy. Epimutations are defined as alterations in the epigenome, i.e., changes in DNA methylation, histone modification and small regulatory RNAs. We are interested in: mechanisms of (epi)mutation induction, for example, during DNA repair, replication or recombination; novel methods of (epi)mutation detection, with a focus on ultra-high-throughput sequencing; the landscape of somatic mutations and epimutations in cancer and aging; the role of de novo mutations in human disease and aging; mutations in population genomics; interactions between mutations and epimutations; the role of epimutations in chromatin structure and function; mitochondrial DNA mutations and their consequences in terms of human disease and aging; and novel ways to generate mutations and epimutations in cell lines and animal models. Of special interest are basic mechanisms through which DNA damage and mutations impact development and differentiation, stem cell biology and cell fate in general, including various forms of cell death and cellular senescence. The study of genome instability in human molecular epidemiology and in relation to complex phenotypes, such as human disease, is considered a growing area of importance. Mutation Research publishes full-length research articles, short research communications, reviews and mini-reviews, Letters to the Editor, book reviews and meeting reports. [1]

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Series / Collection
4 RESULTS in 4 msec
Active ( 1964  -  9999 )

  Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

0027-5107 ( Print )  1386-1964 ( Print )  1873-135X ( Online )  0921-8262 ( Online )  1879-2871 ( Online ) 
Elsevier

847 11907
Active ( 1997  -  9999 )   Mutation Research - Genetic Toxicology and Environmental Mutagenesis

1383-5718 ( Print )  1879-3592 ( Online ) 
Elsevier

343 4425
Inactive ( 1997 - 2001 )   Mutation Research - Mutation Research Genomics

1383-5726 ( Print )  1873-1341 ( Online ) 
Elsevier

8 52
Active ( 1997  -  9999 )   Mutation Research - Reviews in Mutation Research

1383-5742 ( Print )  1388-2139 ( Online ) 
Elsevier

118 1008
Editorial Retractions, Expressions of Concern and External Notices